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glutamyl aminopeptidase

Summary

Gene Symbol

Enpep

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13809

PubChem

13809

Alliance of Genome Resources

MGI:106645

Annotation

Keyword

Aminopeptidase
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying **all 4** entries
UniProt	Protein Name
P16406	Aminopeptidase A BP-1/6C3 antigen
Q8CD51	Aminopeptidase A
Q52JJ6
Q6P3C1

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
angiogenesis	IMP	14998491
angiotensin maturation	IDA	19228697
angiotensin maturation	IMP	16889841
regulation of systemic arterial blood pressure by renin-angiotensin	ISS
regulation of systemic arterial blood pressure by renin-angiotensin	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular process [inference]

cell population proliferation

epithelial cell proliferation [inference]

endothelial cell proliferation [inference]

vascular endothelial cell proliferation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

cell motility [inference]

cell migration

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

glomerulus development

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
cytoplasm	IBA
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	TAS	14998491

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

apical part of cell

side of membrane [inference]

external side of plasma membrane

cluster of actin-based cell projections [inference]

brush border

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
aminopeptidase activity	ISS
aminopeptidase activity	ISO
obsolete glutamyl aminopeptidase activity	IEA
peptidase activity	IDA	14998491
metallopeptidase activity	IDA	19228697

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

amide binding [inference]

peptide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Aminopeptidase N-like , N-terminal domain

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism

Displaying **all 10** entries
Gene Ontology
aminopeptidase activity
hydrolase activity
metal ion binding
metalloaminopeptidase activity
metallopeptidase activity
peptide binding
peptide catabolic process
proteolysis
regulation of blood pressure
zinc ion binding

Ortholog

Displaying entries **31 - 40** of 96 in total

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Species	Gene ID	Orthologous MAtrix
Taeniopygia guttata	100228361	TAEGU24378
Oryctolagus cuniculus	100356733	RABIT05144
Callithrix jacchus	100385544	CALJA28336
Ailuropoda melanoleuca	100465322	AILME14517
Meleagris gallopavo	100542582	MELGA10025
Nomascus leucogenys	100585392	NOMLE14784
Loxodonta africana	100670993	LOXAF14241
Oreochromis niloticus	100702051	ORENI30138
Otolemur garnettii	100960937	OTOGA04966
Pan paniscus	100977323	PANPA30815