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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase with thrombospondin type 1 motif 14
Summary
- Gene Symbol
-
- ADAMTS14
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative promoter usage
- Alternative splicing
- Cleavage on pair of basic residues
- Collagen degradation
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8WXS8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| collagen fibril organization | ||
| collagen catabolic process | ||
| extracellular matrix organization |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:2378 | relapsing-remitting multiple sclerosis | |
| DOID:8398 | osteoarthritis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 237360 | MGI:2179942 | MOUSE01931 | ||
| 309837 | RGD:1308899 | RATNO22016 | ||
| 450513 | 9598_0:002d23 | PANTR00831 | ||
| 489031 | CANLF14647 | |||
| 510214 | BOVIN22481 | |||
| 710154 | MACMU45923 | |||
| 100090634 | ORNAN18193 | |||
| 100225913 | TAEGU26790 | |||
| 100339417 | RABIT06725 | |||
| 100404456 | CALJA07635 |
