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MIRAGE
fucosyltransferase 1

Summary
Gene Symbol
  • Fut1
Organism
Mus musculus (house mouse)
NCBI Gene
14343
KEGG Gene ID
mmu:14343
PubChem
14343
Alliance of Genome Resources
Annotation
Keyword
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid metabolism
  • Proteomics identification
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q32MG3
O09160
  • Alpha(1,2)FT 1
  • Fucosyltransferase 1
  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1
  • Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1
  • Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 18 in total
GO Term Evidence Code PMID
regulation of endothelial cell proliferation
positive regulation of cell-matrix adhesion
positive regulation of cell-matrix adhesion
protein glycosylation
protein glycosylation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
galactoside 2-alpha-l-fucosyltransferase
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 3 entries
Gene Ontology
fucosylation
galactoside 2-alpha-L-fucosyltransferase activity
transferase activity
Displaying 1 entry
InterPro
Glycosyl transferase, family 11
KEGG BRITE Database
Orthology
K00718
Name
galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]
References
Reactions
Displaying entries 11 - 12 of 12 in total
KEGG Reaction Enzyme Acceptor Product
R05968
R06085
Rhea

RHEA:50668

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose
an α-L-Fuc-(1→2)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + H+ + GDP
Enzyme
PMID

RHEA:50664

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose
an α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc derivative + H+ + GDP
Enzyme
PMID

RHEA:32175

a β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1ʼ)-Cer(d18:1(4E)) + GDP-β-L-fucose
H+ + α-L-fucosyl-(1→2)- β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + GDP
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002033
Gene Name
fucosyltransferase 1
Ortholog
Displaying entries 1 - 10 of 44 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
2523 Xenbase:XB-GENE-986117 HUMAN44869
2524 Xenbase:XB-GENE-986117
14343 Xenbase:XB-GENE-986117
14344 Xenbase:XB-GENE-986117
56546 Xenbase:XB-GENE-986117
58924 Xenbase:XB-GENE-986117
81919 Xenbase:XB-GENE-986117 RATNO17310
184168 WB:WBGene00008568
189361 WB:WBGene00021164
281174 BOVIN11468
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025