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Guidelines

MIRAGE

cleavage stimulation factor subunit 3

Summary

Gene Symbol

CSTF3

Organism

Homo sapiens (human)

External Links

NCBI Gene

1479

PubChem

1479

Alliance of Genome Resources

HGNC:2485

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Nucleus
Phosphoprotein
Reference proteome
Repeat
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q12996	CF-1 77 kDa subunit Cleavage stimulation factor 77 kDa subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
RNA 3'-end processing	IBA
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	IDA	7984242

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
mRNA cleavage stimulating factor complex	IDA	7984242

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex [inference]

mRNA cleavage stimulating factor complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
mRNA binding	IBA
protein binding	IPI	7590244

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **51 - 60** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Macaca nemestrina	105471524		MACNE14270
Mandrillus leucophaeus	105528712		MANLE04882
Cercocebus atys	105586778		CERAT16642
Aotus nancymaae	105717253		AOTNA03905
Dipodomys ordii	105988064		DIPOR07652
Sinocyclocheilus grahami	107575522		SINGR05359
Sinocyclocheilus grahami	107602124		SINGR46121
Ictalurus punctatus	108264728		ICTPU27958
Rhinopithecus bieti	108513821		RHIBE14082
Cyprinus carpio carpio	109069419		CYPCA67828

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025