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MIRAGE
interleukin 23 receptor
Summary
- Gene Symbol
-
- IL23R
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Glycoprotein
- Inflammatory response
- Innate immunity
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5VWK5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of T cell mediated cytotoxicity | ||
| positive regulation of defense response to virus by host | ||
| positive regulation of defense response to virus by host | ||
| positive regulation of T-helper 1 type immune response | ||
| positive regulation of T-helper 1 type immune response |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of adaptive immune response [inference]
positive regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of adaptive immune response [inference]
positive regulation of immune response [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| external side of plasma membrane | ||
| cell surface | ||
| receptor complex | ||
| interleukin-23 receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine receptor activity | ||
| prolactin receptor activity | ||
| interleukin-12 receptor binding | ||
| interleukin-12 receptor binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- interleukin-23 receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| interleukin-27 receptor activity |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081120 | Graves ophthalmopathy | |
| DOID:0110883 | inflammatory bowel disease 17 | |
| DOID:0111279 | psoriasis 7 | |
| DOID:10159 | osteonecrosis | |
| DOID:10608 | celiac disease | |
| DOID:11335 | sarcoidosis | |
| DOID:12361 | Graves' disease | |
| DOID:13141 | uveitis | |
| DOID:13241 | Behcet's disease | |
| DOID:2377 | multiple sclerosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 149233 | ZFIN:ZDB-GENE-080107-5 | ||
| 209590 | ZFIN:ZDB-GENE-080107-5 | MOUSE47377 | |
| 609732 | CANLF15616 | ||
| 614367 | BOVIN26759 | ||
| 689932 | RATNO29934 | ||
| 700440 | MACMU22985 | ||
| 733613 | PIGXX30171 | ||
| 744045 | PANTR21334 | ||
| 100053807 | HORSE35118 | ||
| 100081726 | ORNAN09527 |
