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celiac disease
Summary
- Synonym
-
- celiac sprue
- coeliac disease
- idiopathic steatorrhea
- Definition
- An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.
- Super Class
- autoimmune disease of gastrointestinal tract
External Links
- Disease Ontology
- DOID:10608
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 929 | CD14 | CD14 molecule | |
| 1493 | CTLA4 | cytotoxic T-lymphocyte associated protein 4 | |
| 2147 | F2 | coagulation factor II, thrombin | |
| 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3458 | IFNG | interferon gamma | |
| 3569 | IL6 | interleukin 6 | |
| 3586 | IL10 | interleukin 10 | |
| 5444 | PON1 | paraoxonase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12475 | Cd14 | CD14 antigen | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 14061 | F2 | coagulation factor II | |
| 14960 | H2-Aa | histocompatibility 2, class II antigen A, alpha | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | |
| 14969 | H2-Eb1 | histocompatibility 2, class II antigen E beta | |
| 15978 | Ifng | interferon gamma | |
| 16153 | Il10 | interleukin 10 | |
| 18979 | Pon1 | paraoxonase 1 | |
| 54167 | Icos | inducible T cell co-stimulator |
