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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Summary
- Gene Symbol
-
- Ndst1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Hydrolase
- Inflammatory response
- Multifunctional enzyme
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q3UHN9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| inflammatory response | ||
| protein deacetylation |
|
|
| animal organ morphogenesis |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| trans-Golgi network membrane | ||
| Golgi membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| heparan sulfate N-deacetylase activity | ||
| sulfotransferase activity | ||
| deacetylase activity | ||
| [heparan sulfate]-glucosamine N-sulfotransferase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- Functional Category
-
- H: Coenzyme transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| InterPro |
|---|
| Heparan sulfate sulfotransferase |
| Heparan sulphate-N-deacetylase |
| P-loop containing nucleoside triphosphate hydrolase |
| Sulfotransferase domain |
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:0081210 | autosomal recessive intellectual developmental disorder 46 | |
| DOID:1059 | intellectual disability | |
| DOID:11198 | DiGeorge syndrome | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:14227 | azoospermia | |
| DOID:3827 | congenital diaphragmatic hernia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100766710 | 10029_0:001c78 | CRIGR15220 | ||
| 100919030 | SARHA13274 | |||
| 100970863 | PANPA32940 | |||
| 101024920 | PAPAN32492 | |||
| 101044300 | SAIBB23125 | |||
| 101074283 | TAKRU10140 | |||
| 101083399 | FELCA00430 | |||
| 101102810 | SHEEP16934 | |||
| 101127245 | GORGO33744 | |||
| 101155779 | ORYLA01190 |
