newborn respiratory distress syndrome

Summary
Synonym
  • HMD - Hyaline membrane disease
  • Neonatal respiratory Distress syndrome
  • hyaline membrane disease
  • pulmonary hyaline membrane disease
  • pulmonary hypoperfusion syndrome of newborn
  • respiratory distress syndrome of newborn
Definition
A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.
Super Class
respiratory failure
Disease Ontology
DOID:12716
MeSH
UMLS
MGI genotype (from TogoID)
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
847 CAT catalase
6439 SFTPB surfactant protein B
6441 SFTPD surfactant protein D
6647 SOD1 superoxide dismutase 1
387129 NPSR1 neuropeptide S receptor 1
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
15531 Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
22339 Vegfa vascular endothelial growth factor A
The Human Phenotype Ontology
Displaying entries 1 - 10 of 15 in total
HPO ID HPO Term
HP:0002615 Hypotension
HP:0001649 Tachycardia
HP:0012418 Hypoxemia
HP:0000961 Cyanosis
HP:0002878 Respiratory failure
HP:0100750 Atelectasis
HP:0001695 Cardiac arrest
HP:0000765 Abnormal thorax morphology
HP:0002789 Tachypnea
HP:0100598 Pulmonary edema
Displaying 1 entry
Gene ID Gene Symbol Description
6440 SFTPC surfactant protein C

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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