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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pulmonary surfactant-associated protein D
Summary
- UniProt ID
- P35247
- Gene Symbol
-
- SFTPD
- COLEC7
- PSPD
- SFTP4
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P35247
- The Human Metabolome Database
- HMDBP14631
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Coiled coil
- Collagen
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Hydroxylation
- Innate immunity
- Lectin
- Reference proteome
- Repeat
- S-nitrosylation
- Signal
- Surface film
- Gene Ontology (GO)
| GO Term |
|---|
| carbohydrate binding |
| extracellular matrix structural constituent conferring tensile strength |
| identical protein binding |
Sequence
MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 90 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective CSF2RA causes SMDP4 | Homo sapiens |
| Defective CSF2RB causes SMDP5 | Homo sapiens |
| SARS-CoV-1 activates/modulates innate immune responses | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| Surfactant metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050572 | cone-rod dystrophy | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050830 | peripheral artery disease | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis |
