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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
interleukin 1 receptor antagonist
Summary
- Gene Symbol
-
- Il1rn
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin secretion | ||
| negative regulation of glutamate secretion | ||
| immune response | ||
| inflammatory response | ||
| signal transduction |
GO Hierarchy
biological process
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| vesicle | ||
| nucleoplasm | ||
| extracellular space | ||
| centrosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| interleukin-1 receptor antagonist activity | ||
| interleukin-1, type I receptor binding | ||
| interleukin-1 type I receptor antagonist activity | ||
| interleukin-1 type II receptor antagonist activity | ||
| interleukin-1 receptor binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- interleukin-1 receptor antagonist protein
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- M: Cell wall/membrane/envelope biogenesis
| InterPro |
|---|
| Cytokine IL1/FGF |
| Interleukin-1 conserved site |
| Interleukin-1 family |
| Interleukin-1 receptor antagonist/Interleukin-36 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050854 | Muckle-Wells syndrome | |
| DOID:0060645 | chronic recurrent multifocal osteomyelitis | |
| DOID:0080158 | herpes simplex virus keratitis | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080652 | calcium oxalate nephrolithiasis | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:0081120 | Graves ophthalmopathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 105707897 | AOTNA40905 | |||
| 105820330 | PROCO28259 | |||
| 106001191 | 10020_0:0048ce | DIPOR23508 | ||
| 107154168 | 9994_0:0021f9 | |||
| 108541817 | RHIBE36257 | |||
| 109317366 | CROPO24703 | |||
| 109682645 | 51338_0:000db5 | |||
| 110289409 | 10089_0:000b47 | |||
| 110318800 | 10093_0:0012f5 | |||
| 110565344 | 10047_0:004459 |
