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diazepam binding inhibitor, acyl-CoA binding protein

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

1622

PubChem

1622

Alliance of Genome Resources

HGNC:2690

Annotation

Keyword

3D-structure
Acetylation
Alternative promoter usage
Alternative splicing
Direct protein sequencing
Endoplasmic reticulum
Golgi apparatus
Hydroxylation
Lipid-binding
Phosphoprotein
Proteomics identification
Reference proteome
Transport

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A024RAF2
P07108	Diazepam-binding inhibitor Endozepine
B8ZWD8
B8ZWD1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fatty acid metabolic process	IBA
phosphatidylcholine acyl-chain remodeling	IDA	21079819
negative regulation of protein lipidation	IDA	21079819
positive regulation of CoA-transferase activity	IDA	21079819
positive regulation of phospholipid transport	IDA	21079819

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

cellular lipid metabolic process [inference]

fatty acid metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

cellular lipid metabolic process [inference]

fatty acid metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of lipoprotein metabolic process [inference]

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

regulation of lipoprotein metabolic process [inference]

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

regulation of lipoprotein metabolic process [inference]

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

regulation of lipoprotein metabolic process [inference]

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

regulation of lipoprotein metabolic process [inference]

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of protein lipidation [inference]

negative regulation of protein lipidation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of protein lipidation

negative regulation of lipoprotein metabolic process [inference]

negative regulation of protein lipidation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of transferase activity [inference]

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of CoA-transferase activity [inference]

positive regulation of CoA-transferase activity

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	17953517
endoplasmic reticulum lumen	TAS
Golgi apparatus	IDA	17953517 21698759
protein-lipid complex	IDA	21079819
extracellular exosome	HDA	20458337 23533145

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fatty-acyl-CoA binding	IBA
protein binding	IPI	32296183
benzodiazepine receptor binding	TAS	3020548
long-chain fatty acyl-CoA binding	IDA	21079819
identical protein binding	IPI	21079819

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

benzodiazepine receptor binding

identical protein binding

lipid binding [inference]

fatty acid derivative binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

amide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

ion binding [inference]

anion binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

sulfur compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Acyl-CoA-binding domain-containing protein

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
fatty acid metabolic process
fatty-acyl-CoA binding
lipid binding

Displaying **all 4** entries
InterPro
Acyl-CoA binding protein superfamily
Acyl-CoA-binding protein, ACBP, conserved site
Acyl-CoA-binding protein, ACBP
FERM/acyl-CoA-binding protein superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	1622	ZFIN:ZDB-GENE-040426-1861
Mus musculus	13167		MOUSE30870
Rattus norvegicus	25045		RATNO06487
Danio rerio	393831		DANRE45170
Sus scrofa	397212		PIGXX08917
Pan troglodytes	459574		PANTR28535
Macaca mulatta	698652		MACMU06323
Bos taurus	768330		BOVIN24416
Oryctolagus cuniculus	100008823		RABIT11619
Monodelphis domestica	100013541		MONDO25293

GlyTouCan

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UniCarb-DR

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OrthoDB (Group)

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Acknowledgements