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kinesin family member 2A

Summary

Gene Symbol

Kif2a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16563

PubChem

16563

Alliance of Genome Resources

MGI:108390

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Coiled coil
Cytoskeleton
Developmental protein
Differentiation
Lysosome
Microtubule
Mitosis
Motor protein
Neurogenesis
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P28740	Kinesin-2
Q9D481

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
cell division	IEA
mitotic spindle assembly	ISO ISS
cell differentiation	IEA
dendritic transport	IDA IMP	36733270

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

spindle organization [inference]

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

microtubule-based movement

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

cell cycle process [inference]

spindle organization [inference]

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

cellular developmental process [inference]

cell differentiation

cell division

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

spindle organization [inference]

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

dendritic transport

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of cellular process [inference]

regulation of cell motility [inference]

regulation of cell migration

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
microtubule	IBA ISO
spindle	IBA
kinesin complex	IBA
nucleoplasm	ISO
spindle pole	ISO ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

nuclear body

cell junction [inference]

synapse [inference]

GABA-ergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular non-membrane-bounded organelle [inference]

sperm principal piece

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

spindle microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IBA
protein kinase binding	ISO
microtubule binding	IBA IEA ISO
ATP binding	IEA
microtubule motor activity	IBA IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Kinesin-like protein

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription

Displaying **all 7** entries
Gene Ontology
ATP binding
cell cycle
cell division
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding

Displaying **all 5** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0090134	complex cortical dysplasia with other brain malformations 3	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **104** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3796		HGNC:6318	HUMAN79312
Drosophila melanogaster	32049		FB:FBgn0030268
Drosophila melanogaster	37671		FB:FBgn0034824
Drosophila melanogaster	37674		FB:FBgn0034827
Rattus norvegicus	84391	10116_1:000dc7	RGD:70974	RATNO22764
Caenorhabditis elegans	176511		WB:WBGene00002219
Rattus norvegicus	364670	10116_1:004b40
Danio rerio	447926		ZFIN:ZDB-GENE-040912-111
Macaca mulatta	696561			MACMU38830
Bos taurus	768014			BOVIN15886

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Last updated: December 9, 2024