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Repository for lectin-assisted multimodality data
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Guidelines
MIRAGE
methyl CpG binding protein 2
Summary
- Gene Symbol
-
- Mecp2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- DNA-binding
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Z2D6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| behavioral fear response |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of cellular localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of transport [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of multicellular organismal process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of microtubule-based process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| chromatin | ||
| heterochromatin | ||
| heterochromatin | ||
| heterochromatin | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| four-way junction DNA binding | ||
| four-way junction DNA binding | ||
| nucleic acid binding | ||
| DNA binding | ||
| chromatin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Methyl-CpG-binding protein 2
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| chromatin binding |
| double-stranded methylated DNA binding |
| methyl-CpG binding |
| InterPro |
|---|
| DNA-binding domain superfamily |
| Methyl-CpG DNA binding |
| Methyl-CpG binding protein MeCP2/MBD4 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1206 | Rett syndrome |
