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MIRAGE
Methyl-CpG-binding protein 2
Summary
- UniProt ID
- Q9Z2D6
- Gene Symbol
-
- Mecp2
- Gene ID
- 17257
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- DNA-binding
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| heterochromatin |
| nucleus |
| cytoplasm |
| postsynapse |
| nucleoplasm |
| glutamatergic synapse |
| cytosol |
| protein-containing complex |
| centrosome |
| GO Term |
|---|
| chromatin binding |
| promoter-specific chromatin binding |
| four-way junction DNA binding |
| siRNA binding |
| unmethylated CpG binding |
| methyl-CpG binding |
| histone reader activity |
| chromatin DNA binding |
| identical protein binding |
| histone deacetylase binding |
Sequence
MVAGMLGLREEKSEDQDLQGLRDKPLKFKKAKKDKKEDKEGKHEPLQPSAHHSAEPAEAGKAETSESSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTGRPKAAASEGVQVKRVLEKSPGKLVVKMPFQASPGGKGEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVHETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESTKAPMPLLPSPPPPEPESSEDPISPPEPQDLSSSICKEEKMPRGGSLESDGCPKEPAKTQPMVATTTTVAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 86 |
|
|||
| 184 |
|
|||
| 346 |
|
|||
| 434 |
|
|||
| 441 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of MECP2 expression and activity | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1206 | Rett syndrome |
