dihydrolipoamide dehydrogenase
| UniProt | Protein Name |
|---|---|
| E9PEX6 |
|
| A0A024R713 |
|
| P09622 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetyl-CoA biosynthetic process from pyruvate | ||
| acetyl-CoA biosynthetic process from pyruvate | ||
| acetyl-CoA biosynthetic process from pyruvate | ||
| pyruvate metabolic process | ||
| 2-oxoglutarate metabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| oxoglutarate dehydrogenase complex | ||
| oxoglutarate dehydrogenase complex | ||
| pyruvate dehydrogenase complex | ||
| pyruvate dehydrogenase complex | ||
| pyruvate dehydrogenase complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| dihydrolipoyl dehydrogenase activity | ||
| dihydrolipoyl dehydrogenase activity | ||
| protein binding | ||
| pyruvate dehydrogenase (NAD+) activity | ||
| 2-oxoisovalerate dehydrogenase (acylating) activity |
| Gene Ontology |
|---|
| cellular response to oxidative stress |
| flavin adenine dinucleotide binding |
| nucleotide binding |
| oxidoreductase activity |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9269 | maple syrup urine disease |
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000252 | Microcephaly |
| HP:0000708 | Atypical behavior |
| HP:0001250 | Seizure |
| HP:0001251 | Ataxia |
| HP:0001252 | Hypotonia |
| HP:0001254 | Lethargy |
| HP:0001257 | Spasticity |
| HP:0001263 | Global developmental delay |
| HP:0001290 | Generalized hypotonia |
| Disease ID | Disease Name |
|---|---|
| ORPHA:2394 |
|
| OMIM:246900 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1738 | Xenbase:XB-GENE-982851 | ||
| 13382 | Xenbase:XB-GENE-982851 | MOUSE08536 | |
| 298942 | Xenbase:XB-GENE-982851 | RATNO35450 | |
| 397129 | PIGXX36443 | ||
| 399479 | DANRE27563 | ||
| 403978 | CANLF05526 | ||
| 463861 | PANTR41163 | ||
| 533910 | BOVIN27962 | ||
| 700494 | MACMU32777 | ||
| 100050920 | HORSE33518 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025