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Guidelines

MIRAGE

RNA helicase

Summary

Gene Symbol

ddx-19

Organism

Caenorhabditis elegans

External Links

NCBI Gene

174418

PubChem

174418

Alliance of Genome Resources

WB:WBGene00011580

Annotation

Keyword

Helicase
Proteomics identification
Reference proteome

Proteins

Displaying **all 5** entries
UniProt	Protein Name
B7WN80
B7WN81
O18056
Q22308
O62372

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
germ cell development	IGI	19264959
poly(A)+ mRNA export from nucleus	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development

anatomical structure development [inference]

cell development [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IBA
cytoplasmic stress granule	IBA
P granule	IDA	20223759
intracellular organelle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

intracellular organelle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
nucleic acid binding	IEA
RNA helicase activity	IBA
RNA helicase activity	IEA
mRNA binding	IBA
helicase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

RNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding

RNA binding [inference]

mRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity

RNA helicase activity

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

helicase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
hydrolase activity
nucleotide binding
poly(A)+ mRNA export from nucleus

Displaying **all 5** entries
InterPro
DEAD/DEAH box helicase domain
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
P-loop containing nucleoside triphosphate hydrolase
RNA helicase, DEAD-box type, Q motif

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
P granule	PMID:20223759

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	174418	Xenbase:XB-GENE-958136

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025