ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
| UniProt | Protein Name |
|---|---|
| A0A0K3ART9 |
|
| Q86DA5 |
|
| Q5I9W0 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell fate specification | ||
| signal transduction | ||
| cell-cell signaling | ||
| nervous system development | ||
| protein localization |
| GO Term | Evidence Code | PMID |
|---|---|---|
| NAD+ nucleosidase activity | ||
| NAD+ nucleosidase activity | ||
| protein binding | ||
| hydrolase activity | ||
| protein kinase binding |
| Gene Ontology |
|---|
| NAD+ nucleosidase activity |
| hydrolase activity |
| negative regulation of MyD88-independent toll-like receptor signaling pathway |
| response to axon injury |
| signaling adaptor activity |
| Location | References |
|---|---|
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:332 | amyotrophic lateral sclerosis |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 23098 | Xenbase:XB-GENE-6033913 | ||
| 38895 | Xenbase:XB-GENE-6033913 | ||
| 175502 | Xenbase:XB-GENE-6033913 | ||
| 237868 | Xenbase:XB-GENE-6033913 | ||
| 287545 | Xenbase:XB-GENE-6033913 | ||
| 403143 | Xenbase:XB-GENE-6033913 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025