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Glycan Structure Repository

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Glycoconjugate Repository

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Glycomics MS raw data Repository

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Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

Sterile alpha and Armadillo motif

Summary

Gene Symbol

Sarm

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

38895

KEGG Gene ID

PubChem

38895

Alliance of Genome Resources

FB:FBgn0262579

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
signal transduction	IEA
NAD+ catabolic process	IDA
NAD+ catabolic process	IEA
innate immune response
response to axon injury	IMP

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

antiviral innate immune response

cellular process [inference]

signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

purine-containing compound catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine-containing compound catabolic process [inference]

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

NAD+ catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

NAD+ metabolic process [inference]

NAD+ catabolic process

purine-containing compound catabolic process [inference]

purine nucleotide catabolic process [inference]

NAD+ catabolic process

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

NAD+ catabolic process

pyridine-containing compound catabolic process [inference]

pyridine nucleotide catabolic process [inference]

NAD+ catabolic process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

antiviral innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

antiviral innate immune response

response to wounding [inference]

response to axon injury

immune response [inference]

innate immune response

antiviral innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

antiviral innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

antiviral innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
mitochondrion	ISS
cytosol	IDA
axon	IEA
dendrite	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

neuronal cell body

Displaying **all 5** entries
GO Term	Evidence Code	PMID
NAD+ nucleosidase activity	IEA
signaling adaptor activity	IEA
NAD+ nucleosidase activity, cyclic ADP-ribose generating	IDA
NAD+ nucleosidase activity, cyclic ADP-ribose generating	IEA
STAT family protein binding	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

binding [inference]

protein binding [inference]

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

STAT family protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cytosol	PMID:36817462
membrane	FB:FBrf0231198
neuronal cell body	PMID:22678360
neuron projection	PMID:22678360

Rhea

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1289	neurodegenerative disease	Alliance of Genome Resources

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	23098	HGNC:17074
Danio rerio	403143	ZFIN:ZDB-GENE-040219-1
Mus musculus	237868	MGI:2136419
Rattus norvegicus	287545	RGD:1310078
Caenorhabditis elegans	175502	WB:WBGene00006575

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026