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Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4

Summary

Gene Symbol

eat-4

Organism

Caenorhabditis elegans

External Links

NCBI Gene

176291

PubChem

176291

Alliance of Genome Resources

WB:WBGene00001135

Annotation

Keyword

Cell membrane
Glycoprotein
Neurotransmitter transport
Reference proteome
Sodium transport
Symport
Synapse
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
S6DQ91
P34644	Abnormal pharyngeal pumping eat-4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IEA
neurotransmitter transport	IEA
hyperosmotic response	IMP	11717360
adult locomotory behavior	IMP	24094107
response to mechanical stimulus	IMP	11717360

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

multicellular organismal process [inference]

behavior [inference]

locomotory behavior [inference]

adult locomotory behavior

adult behavior [inference]

adult locomotory behavior

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

hyperosmotic response

response to external stimulus [inference]

response to mechanical stimulus

response to abiotic stimulus [inference]

response to osmotic stress [inference]

hyperosmotic response

response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

monoatomic anion transport

neurotransmitter transport

neurotransmitter loading into synaptic vesicle

transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

amide transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

establishment of localization in cell [inference]

neurotransmitter loading into synaptic vesicle

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of backward locomotion

regulation of backward locomotion [inference]

positive regulation of backward locomotion

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of backward locomotion

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of male mating behavior

positive regulation of reproductive process [inference]

positive regulation of male mating behavior

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of behavior [inference]

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

negative regulation of reproductive process [inference]

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

positive regulation of behavior [inference]

positive regulation of male mating behavior

negative regulation of behavior [inference]

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

regulation of feeding behavior [inference]

regulation of eating behavior [inference]

regulation of nematode pharyngeal pumping

regulation of male mating behavior [inference]

regulation of turning behavior involved in mating [inference]

negative regulation of turning behavior involved in mating

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

positive regulation of male mating behavior

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of male mating behavior

negative regulation of multicellular organismal process [inference]

negative regulation of behavior [inference]

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

regulation of reproductive process [inference]

regulation of male mating behavior [inference]

regulation of turning behavior involved in mating [inference]

negative regulation of turning behavior involved in mating

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

positive regulation of male mating behavior

negative regulation of reproductive process [inference]

negative regulation of male mating behavior [inference]

negative regulation of turning behavior involved in mating

positive regulation of reproductive process [inference]

positive regulation of male mating behavior

regulation of biological quality [inference]

regulation of synapse structure or activity

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA
synaptic vesicle membrane	ISS	9870947
synaptic vesicle membrane	IBA
synapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse

excitatory synapse

Displaying **all 5** entries
GO Term	Evidence Code	PMID
L-glutamate transmembrane transporter activity	IBA
neurotransmitter transmembrane transporter activity	IBA
symporter activity	IEA
glutamate:sodium symporter activity	ISS	9870947
transmembrane transporter activity	IEA