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NRAMP-like transporter smf-3

Summary

Gene Symbol

smf-3

Organism

Caenorhabditis elegans

External Links

NCBI Gene

177044

PubChem

177044

Alliance of Genome Resources

WB:WBGene00004878

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Glycoprotein
Iron transport
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q95XG8	DMT-1 Divalent metal transporter smf-3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
transition metal ion transport	ISS	19924247
iron ion transport	IEA
manganese ion transport	IBA
intracellular iron ion homeostasis	IMP	19924247
response to oxidative stress	IMP	15670846

GO Hierarchy

biological process

cellular process [inference]

maintenance of location in cell [inference]

sequestering of iron ion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

manganese ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to oxidative stress

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to chemical [inference]

response to inorganic substance [inference]

response to metal ion

response to manganese ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

transition metal ion transport

iron ion transport

iron ion transmembrane transport

manganese ion transport

manganese ion transmembrane transport

cadmium ion transport [inference]

cadmium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

maintenance of location [inference]

sequestering of metal ion [inference]

sequestering of iron ion

maintenance of location in cell [inference]

sequestering of iron ion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
endosome membrane	IBA
membrane	IEA
apical plasma membrane	IDA	19924247

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
iron ion transmembrane transporter activity	IBA
manganese ion transmembrane transporter activity	IBA
cadmium ion transmembrane transporter activity	IBA
metal ion transmembrane transporter activity	IEA
transition metal ion transmembrane transporter activity	ISS	19924247

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cadmium ion transmembrane transporter activity
manganese ion transmembrane transporter activity
metal ion transmembrane transporter activity

Displaying 1 entry
InterPro
NRAMP family

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
apical plasma membrane	PMID:19924247

Ortholog

Displaying entries **1 - 10** of 11 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	4891	Xenbase:XB-GENE-487563
Danio rerio	6556	ZFIN:ZDB-GENE-021115-1
Danio rerio	18173	ZFIN:ZDB-GENE-021115-1
Xenopus tropicalis	18174	Xenbase:XB-GENE-487563
Xenopus tropicalis	25715	Xenbase:XB-GENE-487563
Xenopus tropicalis	42490	Xenbase:XB-GENE-487563
Xenopus tropicalis	177044	Xenbase:XB-GENE-487563
Xenopus tropicalis	180939	Xenbase:XB-GENE-487563
Xenopus tropicalis	191766	Xenbase:XB-GENE-487563
Danio rerio	316519	ZFIN:ZDB-GENE-021115-1