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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neurofilament, medium polypeptide
Summary
- Gene Symbol
-
- Nefm
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell projection
- Coiled coil
- Cytoskeleton
- Direct protein sequencing
- Glycoprotein
- Intermediate filament
- Methylation
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0R4J036 |
|
| P08553 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| microtubule cytoskeleton organization | ||
| intermediate filament bundle assembly | ||
| neurofilament bundle assembly | ||
| intermediate filament cytoskeleton organization | ||
| neurofilament cytoskeleton organization |
| GO Term | Evidence Code | PMID |
|---|---|---|
| intermediate filament cytoskeleton | ||
| postsynaptic density | ||
| perikaryon | ||
| neurofibrillary tangle | ||
| postsynaptic intermediate filament cytoskeleton |
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| protein-containing complex binding | ||
| structural constituent of cytoskeleton | ||
| toxic substance binding | ||
| structural molecule activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neurofilament medium polypeptide
- Functional Category
-
- D: Cell cycle control, cell division, chromosome partitioning
- M: Cell wall/membrane/envelope biogenesis
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| neurofilament bundle assembly |
| structural constituent of cytoskeleton |
| structural molecule activity |
| InterPro |
|---|
| Intermediate filament head, DNA-binding domain |
| Intermediate filament protein, conserved site |
| Intermediate filament, rod domain |
| Keratin, type I |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11446 | sciatic neuropathy | |
| DOID:1459 | hypothyroidism | |
| DOID:224 | transient cerebral ischemia | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:526 | human immunodeficiency virus infectious disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4741 | HGNC:7734 | HUMAN93056 | ||
| 24588 | 10116_1:0047a9 | RGD:3160 | RATNO10441 | |
| 281347 | BOVIN34762 | |||
| 486111 | CANLF09985 | |||
| 553718 | ZFIN:ZDB-GENE-050522-205 | DANRE20866 | ||
| 711196 | MACMU43932 | |||
| 745196 | PANTR42190 | |||
| 780230 | Xenbase:XB-GENE-6457034 | |||
| 100009343 | RABIT08116 | |||
| 100011103 | MONDO04916 |
