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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Disintegrin and metalloproteinase domain-containing protein 17 homolog
Summary
- Gene Symbol
-
- adm-4
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q94316 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| response to stimulus | ||
| Notch signaling pathway | ||
| membrane protein ectodomain proteolysis | ||
| cell fate specification |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ADAM 17
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| membrane protein ectodomain proteolysis |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050855 | renal fibrosis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:14004 | thoracic aortic aneurysm | |
| DOID:3310 | atopic dermatitis | |
| DOID:6000 | congestive heart failure | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6868 | HGNC:195 | |||
| 11491 | MGI:1096335 | |||
| 43558 | FB:FBgn0039734 | |||
| 57027 | RGD:620404 | |||
| 324142 | ZFIN:ZDB-GENE-030131-2862 | |||
| 560657 | ZFIN:ZDB-GENE-041001-199 | |||
| 9940698 | 7209_0:002438 | |||
| 25340726 | 51031_0:002f37 | |||
| 25340727 | 51031_0:002f6c | |||
| 36385238 | 34506_0:002b77 |
