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MIRAGE
dopamine receptor D2
Summary
- Gene Symbol
-
- DRD2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Golgi apparatus
- Palmitate
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P14416 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| temperature homeostasis | ||
| response to hypoxia | ||
| synaptic transmission, dopaminergic | ||
| response to amphetamine | ||
| nervous system process involved in regulation of systemic arterial blood pressure |
GO Hierarchy
- pigmentation
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
negative regulation of transport [inference]
regulation of neurotransmitter transport [inference]
regulation of amine transport [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
negative regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| dendrite | ||
| synaptic vesicle membrane | ||
| sperm flagellum | ||
| presynaptic membrane | ||
| dendritic spine |
| GO Term | Evidence Code | PMID |
|---|---|---|
| heterocyclic compound binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| adenylate cyclase-activating adrenergic receptor signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:10024 | migraine with aura | |
| DOID:10763 | hypertension | |
| DOID:1596 | depressive disorder | |
| DOID:2030 | anxiety disorder | |
| DOID:251 | alcohol-induced mental disorder | |
| DOID:2559 | opiate dependence | |
| DOID:480 | movement disease | |
| DOID:783 | end stage renal disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100940737 | OTOGA07892 | ||
| 100980993 | PANPA07962 | ||
| 101019372 | PAPAN06662 | ||
| 101049546 | SAIBB06591 | ||
| 101074274 | TAKRU04777 | ||
| 101096838 | FELCA24763 | ||
| 101113525 | SHEEP06093 | ||
| 101152577 | GORGO02408 | ||
| 101164579 | ORYLA03431 | ||
| 101320175 | TURTR02032 |
