GlyCosmos Portal

Submissions

neurexin III

Summary

Gene Symbol

Nrxn3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18191

PubChem

18191

Alliance of Genome Resources

MGI:1096389

Annotation

Keyword

3D-structure
Alternative promoter usage
Alternative splicing
Angiogenesis
Calcium
Cell adhesion
Cell membrane
Cell projection
Disulfide bond
EGF-like domain
Heparan sulfate
Metal-binding
Reference proteome
Repeat
Signal
Synapse
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6P9K9	Neurexin III-alpha Neurexin-3-alpha
Q8C985	Neurexin III-beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 15 in total

« First

‹ Prev

1

2

3
GO Term	Evidence Code	PMID
social behavior	ISO
neurotransmitter receptor localization to postsynaptic specialization membrane	IDA IMP	27133466
angiogenesis	IEA
chemical synaptic transmission	IGI	12827191
trans-synaptic signaling	IDA IMP	26030848

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

trans-synaptic signaling, modulating synaptic transmission

cell adhesion

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to postsynapse [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell periphery [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

postsynaptic specialization assembly [inference]

postsynaptic density assembly

postsynaptic specialization organization [inference]

postsynaptic density organization [inference]

postsynaptic density assembly

postsynaptic specialization assembly [inference]

postsynaptic density assembly

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

organelle assembly [inference]

postsynaptic specialization assembly [inference]

postsynaptic density assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

learning or memory [inference]

learning

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

localization [inference]

protein-containing complex localization [inference]

receptor localization to synapse [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to postsynapse [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell periphery [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

secretion [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of localization in cell [inference]

neurotransmitter secretion

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to postsynapse [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell periphery [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

trans-synaptic signaling, modulating synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of biological quality [inference]

regulation of postsynaptic membrane neurotransmitter receptor levels

neurotransmitter receptor localization to postsynaptic specialization membrane

Displaying entries **6 - 7** of 7 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
glutamatergic synapse	IDA IEP IMP	26030848 27133466 36205393
GABA-ergic synapse	IDA IMP	26030848 35550065

GO Hierarchy

cellular component

protein-containing complex

trans-synaptic protein complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

cell projection

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19816407 29782851
calcium channel regulator activity	IGI	12827191
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

calcium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

neurexin 3

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 6** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site
Laminin G domain
Neurexin/syndecan/glycophorin C
Syndecan/Neurexin domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 79 in total

« First

‹ Prev

1

2

3

4

5

6

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	100379902		Xenbase:XB-GENE-956823
Callithrix jacchus	100404677			CALJA01667
Nomascus leucogenys	100604745			NOMLE21779
Cavia porcellus	100720440	10141_0:002f6b		CAVPO10505
Pan paniscus	100969336			PANPA12452
Papio anubis	101015131			PAPAN36648
Saimiri boliviensis boliviensis	101035539			SAIBB07919
Takifugu rubripes	101064373			TAKRU35085
Felis catus	101087071			FELCA14309
Gorilla gorilla gorilla	101153807			GORGO08710