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pericentriolar material 1

Summary

Gene Symbol

Pcm1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18536

PubChem

18536

Alliance of Genome Resources

MGI:1277958

Annotation

Keyword

Acetylation
Alternative splicing
Cell projection
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9R0L6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
neuron migration	IMP	18762586
centrosome cycle	ISO
centrosome cycle	IEA
interkinetic nuclear migration	IMP	20152126
cytoplasmic microtubule organization	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

microtubule anchoring

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

microtubule-based movement [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

microtubule organizing center organization [inference]

centrosome cycle

cell cycle process [inference]

centrosome cycle

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

microtubule anchoring

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

cilium organization [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

microtubule organizing center organization [inference]

centrosome cycle

supramolecular fiber organization [inference]

cytoplasmic microtubule organization

multicellular organismal process [inference]

behavior [inference]

social behavior

stem cell population maintenance [inference]

neuronal stem cell population maintenance

developmental process [inference]

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

localization [inference]

protein-containing complex localization [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

protein-containing complex localization to centriolar satellite

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

microtubule-based transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

establishment of organelle localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

organelle localization [inference]

nucleus localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

establishment of organelle localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of cellular process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of biological quality [inference]

regulation of protein complex stability

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
pericentriolar material	IDA	20152126 23533177
nucleoplasm	ISO
nucleoplasm	IEA
cytoplasm	IDA	10579718 12571289
centrosome	ISO	24421332

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

cytosol

membrane [inference]

organelle membrane [inference]

nuclear membrane

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16632484 20152126 21565611 24356449 24469809 25088364 27979967
molecular adaptor activity	ISO
molecular adaptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pericentriolar material 1 protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
intraciliary transport involved in cilium assembly
microtubule anchoring at centrosome
protein localization to centrosome

Displaying **all 2** entries
InterPro
Pericentriolar material 1 protein, C-terminal
Pericentriolar material 1 protein

Ortholog

Displaying entries **81 - 82** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122217419		PANLE28002
Ursus americanus	123780415		URSAM15767

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements