proprotein convertase subtilisin/kexin type 2

Summary
Gene Symbol
  • Pcsk2
Organism
Mus musculus (house mouse)
NCBI Gene
18549
PubChem
18549
Alliance of Genome Resources
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Coiled coil
  • Cytoplasmic vesicle
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Proteins
Displaying all 2 entries
UniProt Protein Name
P21661
  • KEX2-like endoprotease 2
  • Prohormone convertase 2
  • Proprotein convertase 2
Q547J8
Gene Ontology (GO)
Displaying entries 6 - 8 of 8 in total
GO Term Evidence Code PMID
islet amyloid polypeptide processing
enkephalin processing
protein processing
GO Hierarchy
OrthoDB (Group)
Group level
Rodentia
Group Name
neuroendocrine convertase 2
Functional Category
  • O: Posttranslational modification, protein turnover, chaperones
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:1574 alcohol use disorder
DOID:5844 myocardial infarction
DOID:784 chronic kidney disease
DOID:9352 type 2 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024