GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
transcription coactivator activity	ISS
transcription coactivator activity	ISO
mRNA binding	IDA	28575669
protein tyrosine kinase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H3T11 kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H3T11 kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

pyruvate kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H3T11 kinase activity

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

hormone binding [inference]

thyroid hormone binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

alkali metal ion binding [inference]

potassium ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription coactivator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Pyruvate kinase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 10** entries
Gene Ontology
ATP binding
catalytic activity
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
phosphorylation
potassium ion binding
pyruvate kinase activity
transferase activity

Displaying **all 9** entries
InterPro
Pyruvate kinase, C-terminal domain superfamily
Pyruvate kinase, C-terminal
Pyruvate kinase, active site
Pyruvate kinase, barrel
Pyruvate kinase, insert domain superfamily
Pyruvate kinase-like domain superfamily
Pyruvate kinase-like, insert domain superfamily
Pyruvate kinase
Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	5313	FB:FBgn0267385
Homo sapiens	5315	Xenbase:XB-GENE-485873	HUMAN23959
Xenopus tropicalis	18746	Xenbase:XB-GENE-485873
Saccharomyces cerevisiae S288C	24651	SGD:S000000036
Xenopus tropicalis	25630	Xenbase:XB-GENE-485873
Xenopus tropicalis	42620	Xenbase:XB-GENE-485873
Danio rerio	335817		DANRE14000
Takifugu rubripes	445901		TAKRU08274
Pan troglodytes	748700		PANTR10715
Xenopus tropicalis	851193	Xenbase:XB-GENE-485873

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Acknowledgements