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MIRAGE
patched 1
Summary
- Gene Symbol
-
- Ptch1
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| branching involved in ureteric bud morphogenesis | ||
| in utero embryonic development | ||
| cell fate determination |
GO Hierarchy
- signal transduction
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| Golgi apparatus | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| patched binding | ||
| smoothened binding | ||
| smoothened binding | ||
| smoothened binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- patched
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hedgehog family protein binding |
| hedgehog receptor activity |
| smoothened binding |
| InterPro |
|---|
| Protein patched/dispatched |
| Sterol-sensing domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050902 | medulloblastoma | |
| DOID:2512 | nevoid basal cell carcinoma syndrome | |
| DOID:2513 | basal cell carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5727 | Xenbase:XB-GENE-488222 | HUMAN97678 | |
| 8643 | FB:FBgn0003892 | ||
| 19206 | Xenbase:XB-GENE-488222 | ||
| 19207 | FB:FBgn0003892 | ||
| 30189 | DANRE43029 | ||
| 35851 | Xenbase:XB-GENE-488222 | ||
| 89830 | RATNO12423 | ||
| 173631 | Xenbase:XB-GENE-488222 | ||
| 174274 | Xenbase:XB-GENE-488222 | ||
| 465254 | PANTR44381 |
