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MIRAGE
protein tyrosine phosphatase, non-receptor type 11
Summary
- Gene Symbol
-
- Ptpn11
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Proteins
| UniProt | Protein Name |
|---|---|
| P35235 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA damage checkpoint signaling |
|
|
| protein dephosphorylation |
|
|
| lipid metabolic process |
|
|
| triglyceride metabolic process |
|
|
| epidermal growth factor receptor signaling pathway |
|
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of cell adhesion [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular component organization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| nucleus |
|
|
| nucleus |
|
|
| nucleoplasm |
|
|
| nucleoplasm |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphotyrosine residue binding |
|
|
| phosphotyrosine residue binding |
|
|
| phosphoprotein phosphatase activity |
|
|
| phosphoprotein phosphatase activity |
|
|
| phosphoprotein phosphatase activity |
|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060250 | idiopathic scoliosis | |
| DOID:0060578 | Noonan syndrome 1 | |
| DOID:0050868 | hepatocellular adenoma | |
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:0014667 | disease of metabolism | |
| DOID:14291 | Noonan syndrome with multiple lentigines | |
| DOID:11984 | hypertrophic cardiomyopathy |
