juvenile myelomonocytic leukemia

Summary
Definition
A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes.
Super Class
myelodysplastic/myeloproliferative neoplasm
Disease Ontology
DOID:0050458
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
867 CBL Cbl proto-oncogene
1437 CSF2 colony stimulating factor 2
3718 JAK3 Janus kinase 3
4763 NF1 neurofibromin 1
5781 PTPN11 protein tyrosine phosphatase non-receptor type 11
9590 AKAP12 A-kinase anchoring protein 12
23092 ARHGAP26 Rho GTPase activating protein 26
Displaying all 4 entries
Gene ID Gene Symbol Description Source
14255 Flt3 FMS-like tyrosine kinase 3
16653 Kras Kirsten rat sarcoma viral oncogene homolog
18015 Nf1 neurofibromin 1
19247 Ptpn11 protein tyrosine phosphatase, non-receptor type 11

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025