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MIRAGE
Rho GTPase-activating protein 26
Summary
- UniProt ID
- Q9UNA1
- Gene Symbol
-
- ARHGAP26
- GRAF
- KIAA0621
- OPHN1L
- Gene ID
- 23092
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell junction
- Chromosomal rearrangement
- Cytoskeleton
- Disease variant
- Endosome
- GTPase activation
- Membrane
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH3 domain
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| cytoskeleton |
| cytosol |
| focal adhesion |
| endosome membrane |
| GO Term |
|---|
| signal transduction |
| regulation of small GTPase mediated signal transduction |
| mitophagy |
| actin cytoskeleton organization |
| GO Term |
|---|
| GTPase activator activity |
| phospholipid binding |
| protein-macromolecule adaptor activity |
Sequence
MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARSSLHAVFSLLVNFVPCHPNLHLLFDRPEEAVHEDSSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 670 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RAC2 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| RHOB GTPase cycle | Homo sapiens |
| RHOC GTPase cycle | Homo sapiens |
| RHOD GTPase cycle | Homo sapiens |
| RHOJ GTPase cycle | Homo sapiens |
| RHOQ GTPase cycle | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0081082 | acute myelomonocytic leukemia |
