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Guidelines

MIRAGE

neurofibromin 1

Summary

Gene Symbol

NF1

Organism

Homo sapiens (human)

External Links

NCBI Gene

4763

PubChem

4763

Alliance of Genome Resources

HGNC:7765

JoGo

NF1

TogoVar

NF1

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell membrane
Disease variant
GTPase activation
Lipid-binding
Nucleus
Phosphoprotein
Proteomics identification
RNA editing
Reference proteome
Tumor suppressor
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P21359	Neurofibromatosis-related protein NF-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **101** in total

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GO Term	Evidence Code	PMID
MAPK cascade	ISS
angiogenesis	IEA
osteoblast differentiation	ISS
metanephros development	ISS
response to hypoxia	ISS

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

myeloid leukocyte migration

cellular process [inference]

cell communication

signal transduction [inference]

cell surface receptor signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

intracellular signal transduction [inference]

MAPK cascade

small GTPase mediated signal transduction [inference]

Ras protein signal transduction

Rac protein signal transduction

phosphatidylinositol 3-kinase/protein kinase B signal transduction

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

peripheral nervous system axon ensheathment [inference]

myelination in peripheral nervous system

myelination [inference]

myelination in peripheral nervous system

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

myeloid cell apoptotic process [inference]

mast cell apoptotic process

neuron apoptotic process

leukocyte apoptotic process [inference]

mast cell apoptotic process

cell population proliferation [inference]

glial cell proliferation [inference]

Schwann cell proliferation

muscle cell proliferation [inference]

smooth muscle cell proliferation [inference]

vascular associated smooth muscle cell proliferation

fibroblast proliferation

epithelial cell proliferation [inference]

endothelial cell proliferation

neural precursor cell proliferation [inference]

neuroblast proliferation

leukocyte proliferation [inference]

mast cell proliferation

stem cell proliferation

actin filament-based process [inference]

actin cytoskeleton organization

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

glial cell differentiation [inference]

oligodendrocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

cell development [inference]

glial cell development [inference]

astrocyte development [inference]

forebrain astrocyte development

Schwann cell development

cell motility [inference]

cell migration [inference]

glial cell migration [inference]

Schwann cell migration

muscle cell migration [inference]

smooth muscle cell migration [inference]

vascular associated smooth muscle cell migration

leukocyte migration [inference]

myeloid leukocyte migration

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

extracellular structure organization [inference]

extracellular matrix organization

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization

collagen fibril organization

supramolecular fiber organization [inference]

collagen fibril organization

export from cell [inference]

secretion by cell [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

observational learning

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

observational learning

visual behavior [inference]

visual learning

molting cycle process [inference]

hair cycle process [inference]

hair follicle maturation

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

forebrain morphogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

hair follicle maturation

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

neural tube development

muscle tissue development [inference]

tube development [inference]

neural tube development

cell development [inference]

glial cell development [inference]

astrocyte development [inference]

forebrain astrocyte development

Schwann cell development

animal organ development [inference]

kidney development [inference]

metanephros development

gland development [inference]

system development [inference]

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

glial cell differentiation [inference]

oligodendrocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

cell development [inference]

glial cell development [inference]

astrocyte development [inference]

forebrain astrocyte development

Schwann cell development

pigmentation

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to heat [inference]

cellular response to heat

response to wounding [inference]

wound healing

cellular response to stress [inference]

cellular response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion [inference]

secretion [inference]

secretion by cell [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion [inference]

acid secretion [inference]

gamma-aminobutyric acid secretion [inference]

gamma-aminobutyric acid secretion, neurotransmission

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

L-amino acid transport [inference]

L-glutamate import [inference]

glutamate secretion, neurotransmission

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion [inference]

gamma-aminobutyric acid secretion, neurotransmission

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

L-amino acid transport [inference]

L-glutamate import [inference]

glutamate secretion, neurotransmission

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion [inference]

gamma-aminobutyric acid secretion, neurotransmission

nitrogen compound transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

L-amino acid transport [inference]

L-glutamate import [inference]

glutamate secretion, neurotransmission

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion [inference]

gamma-aminobutyric acid secretion, neurotransmission

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

amide transport [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

L-glutamate import [inference]

glutamate secretion, neurotransmission

export from cell [inference]

secretion by cell [inference]

glutamate secretion [inference]

glutamate secretion, neurotransmission

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

neurotransmitter secretion [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

positive regulation of immune system process [inference]

positive regulation of mast cell apoptotic process

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration

regulation of mast cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rac protein signal transduction [inference]

negative regulation of Rac protein signal transduction

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway in absence of ligand [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization [inference]

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of smooth muscle cell migration [inference]

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

regulation of vascular associated smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

regulation of glial cell migration [inference]

regulation of Schwann cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of mast cell apoptotic process

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of myeloid cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of neuron apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of stem cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of protein localization [inference]

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rac protein signal transduction [inference]

negative regulation of Rac protein signal transduction

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway in absence of ligand [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis

negative regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of glial cell differentiation

negative regulation of glial cell differentiation [inference]

regulation of astrocyte differentiation [inference]

negative regulation of astrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

negative regulation of oligodendrocyte differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

intracellular signal transduction [inference]

MAPK cascade

small GTPase mediated signal transduction [inference]

Ras protein signal transduction

Rac protein signal transduction

phosphatidylinositol 3-kinase/protein kinase B signal transduction

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rac protein signal transduction [inference]

negative regulation of Rac protein signal transduction

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway in absence of ligand [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion

negative regulation of cell-matrix adhesion

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of stem cell proliferation

regulation of fibroblast proliferation [inference]

negative regulation of fibroblast proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

regulation of vascular associated smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

regulation of glial cell proliferation [inference]

regulation of Schwann cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

regulation of leukocyte proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

regulation of mast cell proliferation [inference]

negative regulation of mast cell proliferation

regulation of stem cell proliferation [inference]

negative regulation of stem cell proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of myeloid cell apoptotic process [inference]

regulation of mast cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of myeloid cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of apoptotic process

positive regulation of myeloid cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of neuron apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of neuron apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of leukocyte apoptotic process [inference]

regulation of mast cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of mast cell apoptotic process

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of extrinsic apoptotic signaling pathway in absence of ligand [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of myeloid cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of neuron apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of glial cell differentiation

negative regulation of glial cell differentiation [inference]

regulation of astrocyte differentiation [inference]

negative regulation of astrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

negative regulation of oligodendrocyte differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of myeloid cell apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of neuron apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of mast cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of stem cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade

negative regulation of MAP kinase activity

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of Rac protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of protein localization [inference]

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of postsynapse organization

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization [inference]

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of smooth muscle cell migration [inference]

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

regulation of vascular associated smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

regulation of glial cell migration [inference]

regulation of Schwann cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration

negative regulation of smooth muscle cell migration [inference]

negative regulation of vascular associated smooth muscle cell migration

negative regulation of glial cell migration [inference]

negative regulation of Schwann cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of tissue remodeling [inference]

regulation of bone remodeling [inference]

regulation of bone resorption

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of gliogenesis [inference]

negative regulation of glial cell differentiation [inference]

negative regulation of glial cell proliferation [inference]

negative regulation of Schwann cell proliferation

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of lyase activity [inference]

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
nucleus	ISS	1550670
nucleoplasm	IDA
nucleolus	IEA
cytoplasm	ISS	1550670
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

presynapse

Displaying **all 4** entries
GO Term	Evidence Code	PMID
GTPase activator activity	IDA	1568247 1570015 2121371
protein binding	IPI	11356864 16374483 23027611 26635368 30194290 34626534
phosphatidylethanolamine binding	IDA	17187824
phosphatidylcholine binding	IDA	17187824

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

ion binding [inference]

cation binding [inference]

phosphatidylcholine binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Neurofibromin

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 7** entries
InterPro
Armadillo-type fold
CRAL-TRIO lipid binding domain superfamily
CRAL-TRIO lipid binding domain
PH-like domain superfamily
Ras GTPase-activating domain
Ras GTPase-activating protein
Rho GTPase activation protein

Disease

Disease Ontology

Displaying **all 10** entries
DO ID	Disease Name	Source
DOID:0050458	juvenile myelomonocytic leukemia	Alliance of Genome Resources
DOID:0070482	spinal neurofibromatosis	Alliance of Genome Resources
DOID:0070483	Watson syndrome	Alliance of Genome Resources
DOID:0111253	neurofibromatosis 1	Alliance of Genome Resources
DOID:0111683	neurofibromatosis-Noonan syndrome	Alliance of Genome Resources
DOID:12849	autistic disorder	Alliance of Genome Resources
DOID:3070	high grade glioma	Alliance of Genome Resources
DOID:4992	optic nerve glioma	Alliance of Genome Resources
DOID:5151	plexiform neurofibroma	Alliance of Genome Resources
DOID:9119	acute myeloid leukemia	Alliance of Genome Resources

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Last updated: December 8, 2025