GlyCosmos Portal

Submissions

Tyrosine-protein kinase JAK3

Summary

UniProt ID

P52333

Gene Symbol

JAK3

Organism

Homo sapiens (human)

External Links

GlyGen: P52333
PubChem: P52333
The Human Metabolome Database: HMDBP01358
The O-GlcNAc Database: P52333

Annotation

Keyword

3D-structure
ATP-binding
Adaptive immunity
Alternative splicing
Cytoplasm
Disease variant
Innate immunity
Membrane
Phosphoprotein
Reference proteome
Repeat
SCID
SH2 domain
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 10** of 33 in total

1

2

3

4

Next ›

Last »
GO Term
adaptive immune response
intracellular signal transduction
regulation of apoptotic process
innate immune response
negative regulation of T cell activation
tyrosine phosphorylation of STAT protein
negative regulation of T-helper 1 cell differentiation
regulation of T cell apoptotic process
negative regulation of thymocyte apoptotic process
response to interleukin-4

Displaying **all 7** entries
GO Term
cytoplasmic side of plasma membrane
extrinsic component of plasma membrane
extrinsic component of cytoplasmic side of plasma membrane
endosome
cytosol
cytoskeleton
plasma membrane

Displaying **all 5** entries
GO Term
growth hormone receptor binding
non-membrane spanning protein tyrosine kinase activity
ATP binding
protein phosphatase binding
protein tyrosine kinase activity

Annotation information from UniProt.

Sequence

MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
792				GlyGen
890			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
Pathway Name	Organism
Interleukin receptor SHC signaling	Homo sapiens
Interleukin-15 signaling	Homo sapiens
Interleukin-2 signaling	Homo sapiens
Interleukin-20 family signaling	Homo sapiens
Interleukin-21 signaling	Homo sapiens
Interleukin-4 and Interleukin-13 signaling	Homo sapiens
Interleukin-7 signaling	Homo sapiens
Interleukin-9 signaling	Homo sapiens
Potential therapeutics for SARS	Homo sapiens
RAF/MAP kinase cascade	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements