Interleukin-7 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
JAK3 inhibitorsJAK3:JAK3 inhibitorsJAK3BRG1WDR9:BRG1BRWD1AcK(9,14,18,79)-p(S10,T11)-histone H3BRWD1:AcK(9,14,18,79)-p(S10,T11)-histone H3p-STAT5p-STAT5 dimerp-STAT5 dimerIL2RGIL2RG:JAK3JAK1IL7R:JAK1IL7RIL7PPBSFSFIL7:IL7R:JAK1IL7:IL7R:JAK1:IL2RG:JAK3ATPADPIL7:IL7R:JAK1:IL2RG:p-JAK3IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3STAT5IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5BIL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5BCISH gene, SOCS1 gene, SOCS2 geneCISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimerCISH,SOCS1,SOCS2p-STAT5 dimer:BRWD1 geneBRWD1 geneRAG1:RAG2 recombinaseRAG1:RAG2 recombinase:Immunoglobulin kappa locusImmunoglobulin kappa locusTSLPIL7R:TSLP:CRLF2CRLF2:IL7RSTAT3IL7R:TSLP:CRLF2:STAT3IL7R:TSLP:CRLF2:p-STAT3p-STAT3IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunitsPI3K regulatory subunitsIRS1,2IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.1

Last updated: February 17, 2025