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MIRAGE
Interleukin-7 receptor subunit alpha
Summary
- UniProt ID
- P16871
- Gene Symbol
-
- IL7R
- Gene ID
- 3575
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- SCID
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| nucleoplasm |
| cytosol |
| external side of plasma membrane |
| clathrin-coated endocytic vesicle membrane |
| GO Term |
|---|
| interleukin-7 receptor activity |
| antigen binding |
| cytokine receptor activity |
Sequence
MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSEDVVITPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 49 | N-linked (GlcNAc...) asparagine |
|
||
| 65 | N-linked (GlcNAc...) asparagine |
|
||
| 151 | N-linked (GlcNAc...) asparagine | |||
| 182 | N-linked (GlcNAc...) asparagine |
|
||
| 232 | N-linked (GlcNAc...) asparagine |
|
||
| 233 | N-linked (GlcNAc...) asparagine |
|
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Interleukin-7 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10534 | stomach cancer | |
| DOID:219 | colon cancer | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:612 | primary immunodeficiency disease | |
| DOID:627 | severe combined immunodeficiency |
