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MIRAGE
ryanodine receptor 2, cardiac
Summary
- Gene Symbol
-
- Ryr2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Calcium channel
- Calcium transport
- Calmodulin-binding
- Developmental protein
- Ligand-gated ion channel
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ||
| response to muscle activity | ||
| response to muscle activity | ||
| calcium-mediated signaling | ||
| calcium-mediated signaling |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| smooth endoplasmic reticulum | ||
| smooth endoplasmic reticulum | ||
| membrane | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ryanodine-sensitive calcium-release channel activity | ||
| ryanodine-sensitive calcium-release channel activity | ||
| ryanodine-sensitive calcium-release channel activity | ||
| calcium channel activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ryanodine receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060675 | catecholaminergic polymorphic ventricular tachycardia 1 | |
| DOID:114 | heart disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6261 | FB:FBgn0011286 | ||
| 6262 | ZFIN:ZDB-GENE-071001-1 | HUMAN55390 | |
| 6263 | FB:FBgn0011286 | ||
| 20190 | FB:FBgn0011286 | ||
| 20191 | ZFIN:ZDB-GENE-071001-1 | ||
| 396856 | PIGXX07478 | ||
| 403615 | CANLF14522 | ||
| 457846 | PANTR24012 | ||
| 689560 | ZFIN:ZDB-GENE-071001-1 | RATNO12911 | |
| 717179 | MACMU21812 |
