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endoglin

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

2022

PubChem

2022

Alliance of Genome Resources

HGNC:3349

Annotation

Keyword

3D-structure
Alternative splicing
Angiogenesis
Cell adhesion
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
P17813
B7Z6Y5
Q5T9B9
F5GX88
Q96CG0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 64 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IDA	18974388
branching involved in blood vessel morphogenesis	ISS	8194490
vasculogenesis	IMP	7894484
vasculogenesis	IBA
response to hypoxia	IDA	18156205

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

central nervous system vasculogenesis

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cardiac epithelial to mesenchymal transition [inference]

cell development [inference]

muscle cell development [inference]

vascular associated smooth muscle cell development

cell motility

cell migration

cell chemotaxis

cell migration involved in heart development [inference]

cell migration involved in endocardial cushion formation

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

export from cell [inference]

secretion by cell [inference]

extracellular matrix constituent secretion

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in blood vessel morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in blood vessel morphogenesis

cardiac chamber morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

aorta morphogenesis [inference]

dorsal aorta morphogenesis

venous blood vessel morphogenesis

branching morphogenesis of an epithelial tube [inference]

branching involved in blood vessel morphogenesis

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

embryonic morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in blood vessel morphogenesis

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

atrial cardiac muscle tissue morphogenesis

ventricular cardiac muscle tissue morphogenesis [inference]

ventricular trabecula myocardium morphogenesis

mesenchyme morphogenesis [inference]

endocardial cushion morphogenesis

cardiac septum morphogenesis [inference]

outflow tract septum morphogenesis

trabecula morphogenesis [inference]

heart trabecula morphogenesis [inference]

ventricular trabecula myocardium morphogenesis

atrioventricular canal morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis [inference]

sprouting angiogenesis

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

smooth muscle tissue development

cell development [inference]

muscle cell development [inference]

vascular associated smooth muscle cell development

animal organ development [inference]

bone development

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

central nervous system vasculogenesis

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cardiac epithelial to mesenchymal transition [inference]

cell development [inference]

muscle cell development [inference]

vascular associated smooth muscle cell development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

response to hypoxia

detection of hypoxia

response to wounding [inference]

wound healing

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to oxygen levels [inference]

detection of oxygen [inference]

detection of hypoxia

response to decreased oxygen levels [inference]

response to hypoxia

detection of hypoxia

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to chemical [inference]

response to xenobiotic stimulus

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of oxygen [inference]

detection of hypoxia

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

extracellular matrix constituent secretion

export from cell [inference]

secretion by cell [inference]

extracellular matrix constituent secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of collagen biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of collagen biosynthetic process [inference]

positive regulation of collagen biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of collagen biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of collagen metabolic process [inference]

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

regulation of collagen biosynthetic process [inference]

positive regulation of collagen biosynthetic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of collagen biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

regulation of cell adhesion

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation

regulation of cell population proliferation

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

regulation of cell proliferation involved in heart morphogenesis

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

regulation of striated muscle cell apoptotic process [inference]

regulation of cardiac muscle cell apoptotic process

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of SMAD protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of blood pressure [inference]

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of oxidoreductase activity [inference]

negative regulation of monooxygenase activity [inference]

negative regulation of nitric-oxide synthase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of oxidoreductase activity [inference]

negative regulation of monooxygenase activity [inference]

negative regulation of nitric-oxide synthase activity

regulation of oxidoreductase activity [inference]

regulation of monooxygenase activity [inference]

negative regulation of monooxygenase activity [inference]

negative regulation of nitric-oxide synthase activity

regulation of nitric-oxide synthase activity [inference]

negative regulation of nitric-oxide synthase activity

negative regulation of oxidoreductase activity [inference]

negative regulation of monooxygenase activity [inference]

negative regulation of nitric-oxide synthase activity

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GO Term	Evidence Code	PMID
extracellular space	IDA	19004009
extracellular space	IBA
plasma membrane	IDA
focal adhesion	HDA	21423176
external side of plasma membrane	IDA	1537377

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

nuclear body

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

blood microparticle [inference]

endothelial microparticle

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	NAS	18974388
transforming growth factor beta receptor activity
type II transforming growth factor beta receptor binding	ISS	8294451
type II transforming growth factor beta receptor binding	IPI	12015308
protein binding	IPI	15702480 20856203 22940691 23868260 28564608 31540324 9872992

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

growth factor binding [inference]

transforming growth factor beta binding

cytokine binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

carbohydrate binding [inference]

monosaccharide binding [inference]

galactose binding

small molecule binding [inference]

monosaccharide binding [inference]

galactose binding

protein-containing complex binding [inference]

activin binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

coreceptor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity

molecular function activator activity [inference]

signaling receptor activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transforming growth factor beta receptor type 3

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
cell migration
epithelial to mesenchymal transition
glycosaminoglycan binding
regulation of transforming growth factor beta receptor signaling pathway
transforming growth factor beta binding
transforming growth factor beta receptor activity
transforming growth factor beta receptor signaling pathway
type II transforming growth factor beta receptor binding
vasculogenesis

Displaying 1 entry
InterPro
Zona pellucida domain

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0060688	arteriovenous malformations of the brain	Alliance of Genome Resources
DOID:10941	intracranial aneurysm	Alliance of Genome Resources
DOID:11294	arteriovenous malformation	Alliance of Genome Resources
DOID:1270	hereditary hemorrhagic telangiectasia	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 47 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2022	Xenbase:XB-GENE-22068377
Mus musculus	13805	Xenbase:XB-GENE-22068377	MOUSE34373
Sus scrofa	397096		PIGXX16232
Rattus norvegicus	497010		RATNO26852
Canis lupus familiaris	609166		CANLF19420
Bos taurus	615844		BOVIN03191
Pan troglodytes	741046		PANTR44904
Monodelphis domestica	100011898		MONDO07334
Pongo abelii	100173392		PONAB36174
Taeniopygia guttata	100226246		TAEGU06418

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements