GlyCosmos Portal

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Endoglin

Summary

UniProt ID

P17813

Gene Symbol

ENG
END

Organism

Homo sapiens (human)

External Links

GlyGen: P17813
PubChem: P17813
The Human Metabolome Database: HMDBP14549
RaftProt: P17813

Annotation

Keyword

3D-structure
Alternative splicing
Angiogenesis
Cell adhesion
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 55 in total

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GO Term
negative regulation of transcription by RNA polymerase II
branching involved in blood vessel morphogenesis
vasculogenesis
epithelial to mesenchymal transition
positive regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
outflow tract septum morphogenesis
endocardial cushion morphogenesis
cardiac ventricle morphogenesis
cardiac atrium morphogenesis

Displaying **all 8** entries
GO Term
focal adhesion
external side of plasma membrane
cell surface
nuclear body
endothelial microparticle
extracellular space
plasma membrane
receptor complex

Displaying entries **1 - 10** of 12 in total

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GO Term
activin binding
identical protein binding
protein homodimerization activity
transforming growth factor beta receptor activity
type II transforming growth factor beta receptor binding
galactose binding
coreceptor activity
type I transforming growth factor beta receptor binding
transforming growth factor beta binding
transmembrane signaling receptor activity

Annotation information from UniProt.

Sequence

MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
88	N-linked (GlcNAc...) asparagine		G45395BF G62765YT	UniProt GlyGen
102	N-linked (GlcNAc...) asparagine			UniProt GlyGen
121	N-linked (GlcNAc...) asparagine			UniProt GlyGen
134	N-linked (GlcNAc...) asparagine	19159218		UniProt GlyGen
307	N-linked (GlcNAc...) asparagine			UniProt GlyGen
334			G57321FI	GlyGen
336			G53434XO	GlyGen
337			G43417UB	GlyGen
343			G53434XO G43417UB	GlyGen
344			G43417UB	GlyGen