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MIRAGE
C-C motif chemokine ligand 2
Summary
- Gene Symbol
-
- Ccl2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Chemotaxis
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| response to hypoxia | ||
| positive regulation of leukocyte mediated cytotoxicity | ||
| positive regulation of leukocyte mediated cytotoxicity | ||
| positive regulation of endothelial cell proliferation |
GO Hierarchy
- response to activity
biological process
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor binding | ||
| cytokine activity | ||
| protein binding | ||
| chemokine activity | ||
| chemokine activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- C-C motif chemokine 2
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10871 | age related macular degeneration |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100379541 | CAVPO14047 | ||
| 100763833 | CRIGR01154 | ||
| 100764122 | CRIGR01157 | ||
| 101589295 | OCTDE13738 | ||
| 101697988 | HETGA07509 | ||
| 101698865 | HETGA07508 | ||
| 101968920 | ICTTR11068 | ||
| 101969207 | ICTTR11069 | ||
| 101973726 | ICTTR11067 | ||
| 102003238 | CHILA18320 |
