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erythropoietin receptor
Summary
- Gene Symbol
-
- EPOR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Congenital erythrocytosis
- Disease variant
- Disulfide bond
- Glycoprotein
- Isopeptide bond
- Phosphoprotein
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P19235 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| brain development | ||
| heart development | ||
| positive regulation of cell population proliferation | ||
| cytokine-mediated signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| nuclear speck |
| GO Term | Evidence Code | PMID |
|---|---|---|
| erythropoietin receptor activity | ||
| erythropoietin receptor activity | ||
| protein binding | ||
| identical protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Erythropoietin receptor
- Functional Category
-
- C: Energy production and conversion
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine-mediated signaling pathway |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060652 | familial erythrocytosis 1 | |
| DOID:2355 | anemia | |
| DOID:3070 | high grade glioma | |
| DOID:8432 | polycythemia | |
| DOID:9074 | systemic lupus erythematosus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2057 | Xenbase:XB-GENE-6459569 | ||
| 13857 | Xenbase:XB-GENE-6459569 | MOUSE63302 | |
| 24336 | RATNO40093 | ||
| 281144 | BOVIN32659 | ||
| 397554 | PIGXX18543 | ||
| 455728 | PANTR17228 | ||
| 484943 | CANLF07833 | ||
| 714546 | MACMU19983 | ||
| 734211 | Xenbase:XB-GENE-6459569 | ||
| 100010880 | MONDO18234 |
