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MIRAGE
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Summary
- Gene Symbol
-
- Slc24a1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Antiport
- Calcium transport
- Cell membrane
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Symport
- Transmembrane helix
- Vision
- Proteins
| UniProt | Protein Name |
|---|---|
| Q91WD8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular calcium ion homeostasis | ||
| intracellular calcium ion homeostasis | ||
| intracellular calcium ion homeostasis | ||
| visual perception | ||
| sodium ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| cell surface | ||
| cell surface |
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium channel activity | ||
| calcium, potassium:sodium antiporter activity | ||
| calcium, potassium:sodium antiporter activity | ||
| calcium, potassium:sodium antiporter activity | ||
| symporter activity |
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
inorganic molecular entity transmembrane transporter activity [inference]
active transmembrane transporter activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium/potassium/calcium exchanger 1
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium channel activity |
| calcium ion transport |
| calcium, potassium |
| intracellular calcium ion homeostasis |
| monoatomic ion transport |
| InterPro |
|---|
| NCX, central ion-binding domain superfamily |
| Sodium/calcium exchanger membrane region |
| Sodium/potassium/calcium exchanger |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110868 | congenital stationary night blindness 1D |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9187 | Xenbase:XB-GENE-991430 | HUMAN23702 | |
| 25769 | FB:FBgn0028704 | ||
| 45248 | Xenbase:XB-GENE-991430 | ||
| 56814 | Xenbase:XB-GENE-991430 | RATNO40109 | |
| 76376 | FB:FBgn0028704 | ||
| 84550 | FB:FBgn0028704 | ||
| 172834 | Xenbase:XB-GENE-991430 | ||
| 214111 | Xenbase:XB-GENE-991430 | ||
| 282474 | BOVIN00482 | ||
| 453521 | PANTR10599 |
