GlyCosmos Portal

Submissions

solute carrier family 24 (sodium/potassium/calcium exchanger), member 1

Summary

Gene Symbol

Slc24a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

214111

PubChem

214111

Alliance of Genome Resources

MGI:2384871

Annotation

Keyword

Antiport
Calcium transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Repeat
Signal
Symport
Transmembrane helix
Vision

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91WD8	Na(+)/K(+)/Ca(2+)-exchange protein 1 Retinal rod Na-Ca+K exchanger Solute carrier family 24 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
calcium ion transmembrane transport	IBA IEA ISO
potassium ion transmembrane transport	IEA ISO
visual perception	IEA
sodium ion transmembrane transport	IEA ISO
long-term synaptic potentiation	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IEA ISO
cell surface	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
symporter activity	IEA
calcium, potassium:sodium antiporter activity	IBA IEA ISO
calcium channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Sodium/potassium/calcium exchanger

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 8** entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
calcium, potassium
intracellular calcium ion homeostasis
monoatomic ion transport
sodium ion transmembrane transport
visual perception

Displaying **all 4** entries
InterPro
NCX, central ion-binding domain superfamily
Sodium/calcium exchanger membrane region
Sodium/potassium/calcium exchanger 1
Sodium/potassium/calcium exchanger

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110868	congenital stationary night blindness 1D	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 75 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9187		HGNC:10975	HUMAN23702
Drosophila melanogaster	45248		FB:FBgn0028704
Rattus norvegicus	56814	10116_1:002e8a	RGD:620080	RATNO40109
Caenorhabditis elegans	172834		WB:WBGene00003569
Bos taurus	282474			BOVIN00482
Pan troglodytes	453521			PANTR10599
Danio rerio	558299		ZFIN:ZDB-GENE-060503-191
Macaca mulatta	713970			MACMU41021
Equus caballus	100066201			HORSE15103
Pongo abelii	100439896			PONAB08841