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F2R like trypsin receptor 1
Summary
- Gene Symbol
-
- F2RL1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Inflammatory response
- Innate immunity
- Palmitate
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P55085 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| establishment of endothelial barrier | ||
| positive regulation of ERK1 and ERK2 cascade | ||
| positive regulation of ERK1 and ERK2 cascade | ||
| positive regulation of ERK1 and ERK2 cascade | ||
| thrombin-activated receptor signaling pathway |
GO Hierarchy
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of glomerular filtration
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in immune response
- positive regulation of chemokine production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of glomerular filtration
biological process
cellular process [inference]
biological process involved in interspecies interaction between organisms [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of pattern recognition receptor signaling pathway [inference]
regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
negative regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular component organization [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of pattern recognition receptor signaling pathway [inference]
regulation of intracellular signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of pattern recognition receptor signaling pathway [inference]
regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cell killing [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cellular component organization [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of vesicle-mediated transport [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| early endosome | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| protein binding | ||
| thrombin-activated receptor activity | ||
| G-protein beta-subunit binding | ||
| signaling receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| positive regulation of Rho protein signal transduction |
| thrombin-activated receptor signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Protease-activated receptor 2 |
| Protease-activated receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060496 | respiratory allergy | |
| DOID:2841 | asthma | |
| DOID:3083 | chronic obstructive pulmonary disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100399992 | CALJA24978 | ||
| 100447792 | PONAB29687 | ||
| 100519703 | PIGXX19277 | ||
| 100543031 | MELGA13389 | ||
| 100579568 | NOMLE25709 | ||
| 100669271 | LOXAF16823 | ||
| 100696035 | ORENI64956 | ||
| 100696301 | ORENI64957 | ||
| 100712829 | CAVPO13293 | ||
| 100719602 | CAVPO13293 |
