coagulation factor III, tissue factor
| UniProt | Protein Name |
|---|---|
| P13726 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of endothelial cell proliferation | ||
| activation of plasma proteins involved in acute inflammatory response | ||
| activation of blood coagulation via clotting cascade | ||
| activation of cysteine-type endopeptidase activity involved in apoptotic process |
|
|
| blood coagulation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| cell surface |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protease binding | ||
| serine-type endopeptidase activity | ||
| cytokine receptor activity | ||
| protein binding | ||
| phospholipid binding |
| Gene Ontology |
|---|
| blood coagulation |
| hemostasis |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
| Interferon/interleukin receptor domain |
| Tissue factor |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080600 | COVID-19 | |
| DOID:0080630 | B-lymphoblastic leukemia/lymphoma | |
| DOID:11247 | disseminated intravascular coagulation | |
| DOID:12531 | von Willebrand's disease |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100655674 | LOXAF05882 | ||
| 100929242 | SARHA06630 | ||
| 100944582 | OTOGA16694 | ||
| 100988955 | PANPA01858 | ||
| 101020385 | PAPAN18888 | ||
| 101030131 | SAIBB21932 | ||
| 101118918 | SHEEP00548 | ||
| 101172202 | ORYLA08880 | ||
| 101322362 | TURTR07721 | ||
| 101586139 | OCTDE11923 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025