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Tissue factor

Summary

UniProt ID

P13726

Gene Symbol

Gene ID

2152

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0015598

GlyConnect

Tissue factor

GlyGen

P13726

PubChem

P13726

Re-Glyco

P13726

Annotation

Keyword

3D-structure
Alternative splicing
Blood coagulation
Disulfide bond
Glycoprotein
Palmitate
Reference proteome
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
serine-type peptidase complex
extracellular space
plasma membrane
membrane
collagen-containing extracellular matrix
external side of plasma membrane
cell surface

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
positive regulation of endothelial cell apoptotic process
activation of blood coagulation via clotting cascade
positive regulation of endothelial cell proliferation
activation of plasma proteins involved in acute inflammatory response
positive regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of TOR signaling
positive regulation of interleukin-8 production
positive regulation of positive chemotaxis
blood coagulation
positive regulation of gene expression

Displaying **all 3** entries
GO Term
protease binding
cytokine receptor activity
phospholipid binding

Annotation information from UniProt.

Sequence

METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
156	N-linked (GlcNAc...) asparagine		G00912UN G60033FS G59626AS G23294PN G37399XV G10486CT G28541PG G39446WN	UniProt GlyGen GlyConnect
169	N-linked (GlcNAc...) asparagine		G27058EU	GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Extrinsic Pathway of Fibrin Clot Formation	Homo sapiens
NGF-stimulated transcription	Homo sapiens

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080600	COVID-19	Alliance of Genome Resources
DOID:0080630	B-lymphoblastic leukemia/lymphoma	Alliance of Genome Resources
DOID:11247	disseminated intravascular coagulation	Alliance of Genome Resources
DOID:12531	von Willebrand's disease	Alliance of Genome Resources