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MIRAGE
coagulation factor VII
Summary
- Gene Symbol
-
- F7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydroxylation
- Pharmaceutical
- Proteomics identification
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| positive regulation of leukocyte chemotaxis | ||
| positive regulation of leukocyte chemotaxis | ||
| blood coagulation | ||
| blood coagulation |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| endoplasmic reticulum lumen | ||
| Golgi lumen | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| signaling receptor binding | ||
| calcium ion binding | ||
| protein binding | ||
| serine-type peptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:1588 | thrombocytopenia | |
| DOID:2215 | factor VII deficiency | |
| DOID:2913 | acute pancreatitis | |
| DOID:3393 | coronary artery disease | |
| DOID:3526 | cerebral infarction | |
| DOID:5844 | myocardial infarction | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9744 | type 1 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2155 | Xenbase:XB-GENE-5787186 | ||
| 14068 | Xenbase:XB-GENE-5787186 | MOUSE57886 | |
| 260320 | Xenbase:XB-GENE-5787186 | RATNO10874 | |
| 607661 | CANLF08867 | ||
| 617960 | BOVIN04159 | ||
| 733661 | PIGXX01551 | ||
| 100022420 | MONDO31773 | ||
| 100223776 | TAEGU11138 | ||
| 100410381 | CALJA20944 | ||
| 100471728 | AILME01104 |
