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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase with thrombospondin type 1 motif 2
Summary
- Gene Symbol
-
- Adamts2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Collagen degradation
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8C9W3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| collagen fibril organization | ||
| lung development | ||
| spermatogenesis | ||
| collagen catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| collagen-containing extracellular matrix | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metalloendopeptidase activity | ||
| peptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Zinc finger, RING-type
- Functional Category
-
- D: Cell cycle control, cell division, chromosome partitioning
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
| InterPro |
|---|
| Thrombospondin type-1 (TSP1) repeat |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080733 | Ehlers-Danlos syndrome dermatosparaxis type | |
| DOID:13359 | Ehlers-Danlos syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 9509 | HGNC:218 | HUMAN82655 | ||
| 282401 | BOVIN32058 | |||
| 287899 | 10116_1:0038af | RGD:1565950 | RATNO01803 | |
| 462325 | PANTR37001 | |||
| 481453 | CANLF01981 | |||
| 571682 | ZFIN:ZDB-GENE-070816-3 | |||
| 100029340 | MONDO09178 | |||
| 100224296 | TAEGU04132 | |||
| 100395899 | CALJA26948 | |||
| 100447800 | PONAB29254 |
