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MIRAGE
transforming growth factor, beta receptor I
Summary
- Gene Symbol
-
- Tgfbr1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Isopeptide bond
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Tight junction
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| skeletal system development | ||
| angiogenesis | ||
| in utero embryonic development | ||
| kidney development | ||
| blastocyst development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| transforming growth factor beta binding | ||
| transforming growth factor beta receptor activity, type III | ||
| I-SMAD binding | ||
| I-SMAD binding | ||
| BMP receptor activity |
GO Hierarchy
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
catalytic activity, acting on a protein [inference]
binding [inference]
molecular transducer activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- kinase
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| nucleotide binding |
| transmembrane receptor protein serine/threonine kinase activity |
| transmembrane receptor protein serine/threonine kinase signaling pathway |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050466 | Loeys-Dietz syndrome | |
| DOID:418 | systemic scleroderma | |
| DOID:8398 | osteoarthritis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115607974 | STRHB15283 | ||
| 116440876 | CORMO08177 | ||
| 116828720 | CHEAB10775 | ||
| 118896926 | BALMU13605 | ||
| 122205665 | PANLE25355 | ||
| 123781069 | URSAM00847 |
