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Repository for lectin-assisted multimodality data
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MIRAGE
TGF-beta receptor type-1
Summary
- UniProt ID
- Q64729
- Gene Symbol
-
- Tgfbr1
- Gene ID
- 21812
- Organism
- Mus musculus (house mouse)
External Links
- PubChem
- Q64729
- The Human Metabolome Database
- HMDBP14494
- Re-Glyco
- Q64729
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Isopeptide bond
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Tight junction
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| membrane |
| endosome |
| cell surface |
| caveola |
| bicellular tight junction |
| membrane raft |
| transforming growth factor beta ligand-receptor complex |
| nucleus |
| plasma membrane |
Sequence
MEAAAAAPRRPQLLIVLVAAATLLPGAKALQCFCHLCTKDNFTCETDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGAVTTTYCCNQDHCNKIELPTTGPFSEKQSAGLGPVELAAVIAGPVCFVCIALMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 41 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of TGF-beta receptor signaling | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Mus musculus |
| TGFBR3 regulates TGF-beta signaling | Mus musculus |
| Ub-specific processing proteases | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050466 | Loeys-Dietz syndrome | |
| DOID:418 | systemic scleroderma | |
| DOID:8398 | osteoarthritis |
