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toll-like receptor 6

Summary

Gene Symbol

Tlr6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21899

PubChem

21899

Alliance of Genome Resources

MGI:1341296

Annotation

Keyword

3D-structure
Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Golgi apparatus
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9EPW9
Q3UV88

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **31 - 32** of 32 in total

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GO Term	Evidence Code	PMID
microglial cell activation	ISO
cellular response to diacyl bacterial lipopeptide	IBA ISO

GO Hierarchy

biological process

immune system process

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response

innate immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

metabolic process [inference]

nitrogen compound metabolic process [inference]

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipoprotein

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipopeptide [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to diacyl bacterial lipopeptide [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to biotic stimulus [inference]

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipoprotein

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipopeptide [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to diacyl bacterial lipopeptide [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipoprotein

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

response to bacterial lipopeptide [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to diacyl bacterial lipopeptide [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of bacterial lipoprotein [inference]

detection of bacterial lipopeptide [inference]

detection of diacyl bacterial lipopeptide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to bacterial lipoprotein [inference]

cellular response to bacterial lipopeptide [inference]

cellular response to diacyl bacterial lipopeptide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor 2 signaling pathway

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

negative regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

negative regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

negative regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor 2 signaling pathway

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

toll-like receptor TLR6:TLR2 signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

negative regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of nitric oxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 2 signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

negative regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-8 production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
receptor complex	ISO
plasma membrane	IBA
phagocytic vesicle membrane
membrane	IEA
Golgi apparatus	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

Toll-like receptor 2-Toll-like receptor 6 protein complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

Toll-like receptor 2-Toll-like receptor 6 protein complex

cellular anatomical entity [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
lipopeptide binding	IBA IMP ISO	11431423
diacyl lipopeptide binding	IDA	19931471
NAD+ nucleotidase, cyclic ADP-ribose generating
signaling receptor binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity [inference]

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

protein binding

signaling receptor binding

Toll-like receptor binding [inference]

Toll-like receptor 2 binding

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

lipid binding [inference]

lipopeptide binding

diacyl lipopeptide binding

amide binding [inference]

peptide binding [inference]

lipopeptide binding

diacyl lipopeptide binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 10** entries
DO ID	Disease Name	Source
DOID:0060000	infective endocarditis	Alliance of Genome Resources
DOID:13564	aspergillosis	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:399	tuberculosis	Alliance of Genome Resources
DOID:4194	glucose metabolism disease	Alliance of Genome Resources
DOID:4483	rhinitis	Alliance of Genome Resources
DOID:612	primary immunodeficiency disease	Alliance of Genome Resources
DOID:854	collagen disease	Alliance of Genome Resources
DOID:8677	perinatal necrotizing enterocolitis	Alliance of Genome Resources
DOID:874	bacterial pneumonia	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 74 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Canis lupus familiaris	119876150		CANLF12266
Vulpes vulpes	112919276		VULVU01221
Ursus americanus	123804286		URSAM09856
Ailuropoda melanoleuca	100472456		AILME03610
Mustela putorius furo	101680311		MUSPF08510
Felis catus	493662		FELCA08631
Panthera leo	122218315		PANLE27144
Tursiops truncatus	101320069		TURTR05124
Loxodonta africana	100672524		LOXAF13381
Equus caballus	100064554		HORSE30757

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Last updated: August 19, 2024