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transformation related protein 53
Summary
- Gene Symbol
-
- Trp53
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Apoptosis
- Biological rhythms
- Cell cycle
- Cytoplasm
- Cytoskeleton
- DNA-binding
- Disease variant
- Endoplasmic reticulum
- Isopeptide bond
- Metal-binding
- Methylation
- Mitochondrion
- Necrosis
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repressor
- Transcription regulation
- Tumor suppressor
- Ubl conjugation
- Zinc
- Proteins
Gene Ontology (GO)
GO Hierarchy
- cell cycle
- viral process
- positive regulation of cell cycle
- negative regulation of cell growth
- positive regulation of cell cycle
- negative regulation of cell growth
- positive regulation of cell cycle
biological process
immune system process [inference]
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cell activation [inference]
signal transduction [inference]
intracellular signal transduction [inference]
apoptotic signaling pathway
cellular metabolic process [inference]
cellular response to stimulus [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of programmed cell death [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of cell population proliferation
negative regulation of cellular metabolic process [inference]
negative regulation of cell cycle [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
intracellular signal transduction [inference]
apoptotic signaling pathway
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of programmed cell death [inference]
negative regulation of cellular process [inference]
negative regulation of cell population proliferation
negative regulation of cellular metabolic process [inference]
negative regulation of cell cycle [inference]
regulation of cellular component organization [inference]
regulation of cell cycle
regulation of mitotic cell cycle
regulation of cell cycle process [inference]
negative regulation of cell cycle process [inference]
regulation of cell cycle phase transition [inference]
negative regulation of cell cycle [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ATP-dependent DNA/DNA annealing activity | ||
| enzyme binding | ||
| protein self-association |
|
|
| MDM2/MDM4 family protein binding | ||
| protein phosphatase 2A binding |
GO Hierarchy
molecular function
binding [inference]
protein binding
organic cyclic compound binding [inference]
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0001816 | angiosarcoma | |
| DOID:0002116 | pterygium | |
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050834 | CHARGE syndrome | |
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0050866 | oral squamous cell carcinoma | |
| DOID:0050902 | medulloblastoma | |
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0060071 | pre-malignant neoplasm |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7157 | HGNC:11998 | HUMAN31534 | |
| 403869 | CANLF15465 | ||
| 112924853 | VULVU18753 | ||
| 123792132 | URSAM24680 | ||
| 101677794 | MUSPF10133 | ||
| 493847 | FELCA32207 | ||
| 122206426 | PANLE05212 | ||
| 101319146 | TURTR13573 | ||
| 118886638 | BALMU11487 | ||
| 100062044 | HORSE03645 |
